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But being present in a cancer cell is not the same as driving the cancer

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Similarly, mice that lack ABHD5 in BAT have normal cold-induced thermogenesis and are not cold-sensitive, but deletion of ABHD5 in both WAT and BAT imparts cold sensitivity in the fasted state (103)

During the pathogenesis of OA, JUN directly binds to the promoter of NCOA4 and initializes its transcription, increasing ferritinophagy degradation, leading to ferroptosis and extracellular matrix degradation in chondrocytes

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