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Initial Loading Phase: Daily Injections The first step is key to quickly fixing Vitamin B12 levels

When cirrhosis develops, a state of hepatic GH resistance ensues resulting in high GH and low IGF-I levels (125) ( Figure 1E )

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IGF-1 Des lacks the first three amino acids at the N-terminus of IGF-1, which makes it more potent and bioavailable compared to IGF-1