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They fall for a Fool's Gold Standard of heart enlargement Dumbing-down diagnosing heart enlargement puts our cavaliers at high risk For the past 9 years (as of 2025), beginning with publication of the EPIC Study report in September 2016, numerous ACVIM board certified veterinary cardiologists have published articles in which they have defined left-sided cardiomegaly (heart enlargement) for any dog of any breed by two minimum echocardiograph measurements, one of the left atrium (LA/Ao = 1.6) and the other of the left ventricle (LVIDDN = 1.7)

doi:10.1080/13803395.2014.904844CrossRefGoogle ScholarPubMed Zamzow, RM, Ferguson, BJ, Stichter, JP, et al

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Contraceptive Implant

Primary results at 80 weeks All three doses met the primary and all key secondary endpoints of the trial