Your provider can help assess whether stopping is appropriate, discuss alternative options, and develop a transition plan
COMPARISON Category Ipamorelin CJC-1295 Half-life 2-3 hours 6-8 days Injection frequency 2-3x daily 2x weekly GH release pattern Pulsatile (spikes) Steady elevation Time to peak 30-45 minutes Gradual over days Best timing Morning, post-workout, bedtime Anytime (long-lasting) Flexibility High (can time around meals) Low (always active) Hunger increase Mild (ghrelin mimetic) Minimal Sleep quality Excellent Very good Muscle growth Good Good Fat loss Good Very good Recovery Excellent Very good Anti-aging Excellent Excellent Cortisol impact None None CHOOSE Don't want daily injections Want maximum GH optimization Budget allows ($200-300/month) FREE TOOLS FAQ Which one is better for muscle growth
Colesevelam, which requires a much lower quantity of drug because of its high affinity and binding capacity for bile salts, has less of an effect on the absorption of other drugs than other bile acid sequestrants but can still adversely affect the absorption of certain drugs (Table 30) (424)
This makes it unique compared to medications like Sildenafil (Viagra) or Tadalafil troches, which primarily improve blood flow
Laskowski, R
Prommer used 2.5mg tirzepatide (half a 5mg pen), genuinely below the therapeutic range
