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Regular exposure to high lipid loads, even before structural changes occur in visceral adipose tissue, leads to inflammatory responses and microvascular dysfunction [34]

Caution is advised when combined with ACEinhibitors, as DSIP is rapidly degraded by aminopeptidases Potential side effects include injection site irritation, headache, vivid dreams, and hormonerelated effects

Like all drugs, it does have side effects, including nausea, diarrhea, and fatigue

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Safety/Tolerability: Common side effects are gastrointestinal (nausea, diarrhea)manageable but notable

Diabetes Care 44(Suppl 1):S111S124 Medici A Diabetologi (AMD) Societ Italiana di Diabetologia (SID) Standard italiani per la cura del diabete mellito 2018