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In a 2018 study, researchers found that 60 minutes of moderate to vigorous exercise each day (walking, jogging, cycling) helped preserve lean mass and VO2max during caloric restriction

Moreau B

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Environmental factors such as heavy metal toxicity [1012], sub-clinical viral infections [13] and gastro-intestinal pathology [14, 15], as well as endogenous toxins produced by metabolic processes [16], hormones (reviewed in [17]) and gastro-intestinal bacteria [18, 19] have also been suggested as playing a role in the aetiology of the disorder, although none of these have been thoroughly investigated

Glutathione is also needed for different chemical processes in the body