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Intranasal administration of edaravone nanoparticles improves its stability and brain bioavailability
[182] developed a polymeric micelle (PM) based on a cyclic peptide moiety(NGR) that can deliver xanthatin (XT) to DCs
however, excessive dosing may result in exaggerated pharmacological effects
Notably, researchers observed that the rise in p21 levels, a marker of senescence, was independent of p53, indicating that, unlike many previous drugs, AKI603-induced senescence may operate independently of p53 activity [79]
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