is glp-1 safe to use vs. GLP-1 + GIP: What's the Difference for your Metabolism? Pulmonary Aspiration Warning for GLP-1

Hum Reprod 33(9):16021618

Keep your diet flexible so you can stay consistent, and use supplements where theyre needed

15 Phase II trials targeting MASH have shown that treatment with SEMA 0.4 mg daily for 72 weeks resulted in more patients with liver fibrosis stage F2/F3 achieving improvement in MASH without progression of liver fibrosis (odds ratio = 6.87, 95% CI = 2.6017.63) compared to placebo

Phase 3 TRANSCEND-T2D-1 (March 19, 2026) showed 16.8% loss at 12 mg over 40 weeks in adults with type 2 diabetes

28.7 percent for 12 mg, but 12 mg had a higher GI dropout rate

Exercise, especially resistance training, is strongly encouraged while on GLP-1 medications