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Before reaching for a bottle, it is essential to look at your daily foundations

Methodological Considerations in Antioxidant Research Despite numerous studies, significant methodological limitations hamper definitive conclusions about efficacy

While the pharmacological inhibition of G6PD clearly shows a detrimental effect on cardiomyocyte function, the effect of a reduction in the enzyme activity due to genetic causes is unknown, although it may presumably be less intense

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Results The PiP-MS method identifies 20S substrates within native lysates To unravel the identity of 20S proteasome substrates in a systematic manner, we established the Proteasome induced Proteolysis coupled-mass Spectrometry (PiP-MS) approach, which is based on the LiPMS workflow (Feng et al, 2014