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Two 10-year case-control studies over very large samples of people with diabetes ( N = 360,205 and N = 73,869, respectively) equally observed no association between GLP-1RA use and incident depression 202,203

The thigh and upper arm are solid alternatives when the abdomen needs rest

2 But as therapeutic use expands, so does our understanding of the complex physiological adaptations these drugs invoke

Over the last few years, the popularity of taking GLP-1 medications for weight loss has greatly increased

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The timing question here is about cessation rather than dosing