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Research suggests fixed doses provide adequate tissue exposure regardless of body size within normal ranges

5 Department of Medicine and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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Doctors often assume that if the pituitary is functioning and telling the thyroid gland to produce thyroid hormones (via TSH), there will be adequate amounts of active thyroid hormone in the body, and that everything is fine

For continuous outcomes, we calculated mean differences and 95% CIs using an inverse variance random-effects model