Gastrointestinal effects nausea, vomiting, diarrhea, and constipation are the most common and can be amplified when two appetite-suppressing compounds are used together
As you can see, the key is little and often
Vitamin B12 does have the potential to react with certain medications including chloramphenicol, proton pump inhibitors, H2 receptor antagonists, and Metformin
Kanemura T, Tamaoki J, Horii S, Sakai N, Kobayashi K, Isono K, Takeuchi S, Takizawa T
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The absence of immunoglobulin A in F11r(+/+)Igha(/) mice did not affect disease, whereas F11r(/)Igha(/) mice displayed markedly increased susceptibility to acute, injury-induced colitis