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Yin et al., 2025)

Several transition metal ions can catalyze Fenton and Fenton-like reactions to produce hydroxyl radicals (OH) and kill cancer cells in the TME

Similarly, ovarian oxidative stress model mice exhibit inhibition of the Nrf2/HO-1/GPX4 pathway (Niu et al., 2023), suggesting that GPX4 deficiency-induced ferroptosis may contribute to reduced ovarian reserve

Stefani, M