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In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment

Science (2001) 291:31922

Its small size and copper-binding affinity underpin its bioactivity, distinguishing it from larger proteins or synthetic peptides

But as you saw, the scientific literature shows that treatment with massive doses of B12, leading to very high blood levels, is 100% safe

Young, A., Gedulin, B., Vine, W., Percy, A

When you swallow a traditional glutathione tablet, the acids and enzymes in your stomach often break the molecule apart before it can be absorbed