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Chang TT, Liaw YF, Wu SS, et al

Conversion of levodopa to dopamine in serotonergic neurons followed by dysregulated dopamine release may play a role in the pathogenesis of LIDs [136]

Any hydration deficit or electrolyte abnormalities should be corrected before the anesthesia that is often required to remove the obstructing feces

While 2,000 mg is often well-tolerated, it is not a "one size fits all" recommendation

The search was performed in multiple databases, including PubMed, Web of Science, and Embase, and was supplemented by manual searches using Google Scholar to ensure completeness

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