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To label specific cell populations at the placode and the hair peg stages, pregnant mice were administered a single dose of Tamoxifen at E17.5 and labeling patterns were established 48 hr latter at P1 when the primary central follicle is at the hair peg stage and the secondary outer follicles are at the placode stage

1 Introduction Tumor-associated macrophages (TAMs), a dominant immune cell population in the tumor microenvironment (TME), significantly influence cancer progression ( Ferroptosis represents a metabolically driven form of regulated cell death that is fundamentally distinct from apoptosis, necroptosis, and pyroptosis ( Figure 1

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