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In clinical studies, participants taking semaglutide GLP-1 lost more weight on average than those taking liraglutide or other GLP-1 medications

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Non-peptidomimetic inhibitors are structurally diverse but common key interactions with DPP4 can be observed

Kinetic parameters were determined using LineweaverBurk plots using KaleidaGraph 4 (Synergy Software, least squares best fit of data and varying concentrations of one substrate while maintaining the concentration of other substrates

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