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Beyond the natural aging process, factors like UV exposure, pollution, and the metabolic stress of intense exercise can lead to "oxidative stress." This stress produces free radicals that can physically break down collagen fibers

[Google Scholar] 53.Jara A., Rodriguez Y., Cornejo J., Cazar M., Gutierrez M., Astudillo L

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McEwan P, Foos V, Palmer JL, Lamotte M, Lloyd A, Grant D

Hence, the therapeutic effect of antidepressants aimed to increase their availability