dr. tyna moore glp-1 I was recently joined by and Calley Means on The Doctor's Farmacy for a controversial discussion of agonists like Ozempic, weighing the pros and cons of these peptides Personalized GLP-1s for Body, Brain

A recent meta-analysis encompassing 11 observational and case-control studies across various countries revealed no statistically significant disparity in suicidal outcomes between GLP-1 RA users and those utilizing alternative antihyperglycemic medications (relative risk, 0.57

Thigh injections can be slightly more uncomfortable than abdominal injections for some people because the thigh has more nerve endings near the surface

A group of researchers, including oncologists and data scientists, from the University of Florida and Indiana University hypothesized that GLP-1s hold promise in oncology due to their ability to lower glucose, adiposity, insulin resistance, and systemic inflammation factors associated with cancer progression, according to a July 2025 paper published in JAMA

In this sense, they may be thought of as disease-modifying agents instead of glucose-lowering therapy

(1:11:27) Addressing the autoimmune crisis

Conclusion: If youve noticed changes in your legs after GLP-1 weight loss, youre not alone