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The targeting sequences used were show in Supplementary Table 1
[8] [9] [10] [11] Although reduced GLP-1 secretion has previously been associated with attenuated incretin effect in patients with type 2 diabetes, further research indicates that GLP-1 secretion in patients with type 2 diabetes does not differ from healthy subjects
Macronutrients determine body composition
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This gradual escalation minimizes gastrointestinal adverse effects such as nausea, vomiting, and diarrhea, which are the most common reasons for treatment discontinuation