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In trials, participants on the highest dose lost an average of 20.9% body weight

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Regarding supplementing with B12, you have two main options: B12 Pills vs B12 Shots

Patients should be aware that Ozempic carries risks of hypoglycaemia (particularly when used with insulin or sulfonylureas), and may potentially worsen diabetic retinopathy, especially with rapid improvement in blood glucose control

The most rigorous bone-specific RCT to date - Hansen et al

Approximately 8.5% of adults had diabetes in 2014, and diabetes was the direct cause of 1.5 million deaths and 48% of those deaths occurred before the age of 70 years in 2019 (14)