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These osteocartilaginous outgrowths form at the joint margins at the interface of the synovium, periosteum, and articular cartilage, yet their development is tightly linked to the mechanical and molecular alterations occurring in the subchondral region (Li et al., 2013)

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The gradient was 0 min, 100% B

muciniphila can strengthen intestinal barrier function and modulate host immune signaling through defined microbial surface molecules 104

10.34172/mj.2021.022 38

The chemistry of curcumin: from extraction to therapeutic agent