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One innovation getting attention is the transdermal GLP-1 patch

Dietary Modifications: Balanced Diet: A nutrient-rich diet emphasizing whole, unprocessed foods, including vegetables, lean proteins, and healthy fats, supports metabolic health while minimizing sugar and refined carbohydrates

Weight loss with these medications does not equal a cure

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However, advances in biased agonism, region-selective delivery, and patient stratification suggest that selective modulation of central peptide pathways may be achievable without broad neuropsychiatric disruption