doi: 10.1016/j.ijid.2021.11.009 8 De DomenicoM
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This mechanism functions independently of the canonical GPX4GSH axis, offering a parallel ferroptosis-suppressive pathway
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Out of various reasons of appearance of drug resistance, genome plasticity is another key factor in the survival of Leishmania parasites and their development of drug resistance in which genetic variations such as mutations, gene amplifications, and chromosomal rearrangements play crucial roles in the appearance of resistance (Kamran et al., 2023)
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