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Studies show that IDH1/2 syntheses isocitrate/citrate from -KG with NADPH consumption, then the isocitrate/citrate import into the mitochondria and contribute to suppress mitochondrial ROS

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Sanders noted that seven new GLP-1based drugs are currently in development, and emerging data suggest possible benefits for neurodegenerative diseases like Alzheimers and Parkinsons

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In: Drug Reimbursement Review sponsor submission: Rybelsus (oral semaglutide), 7 mg and 14 mg tablets