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In ESCC, high preoperative CRP levels are significantly associated with a higher incidence of postoperative complications, especially infectious complications and anastomotic leakage (87, 88)

Third, there is evidence of successful restoration of aberrant mRNA splicing in non-NDD muscular conditions such as Spinal Muscular Atrophy (SMA) [89] and Duchenne Muscular Dystrophy (DMD) [90] through targeting splice junctions and cis-regulatory elements with ASOs [91, 92] (Fig

[1] Three types of this enzyme exist in humans: CPT IA (Found in the liver), CPT IB (found in the muscle), and CPT IC (found in the brain)

Pharmaceutics 12 (11), 1084

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