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Resmetirom (Rezdiffra) is currently the only FDA-approved MASH therapy, with about 26 to 30% resolution in MAESTRO-NASH (Harrison et al

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Additionally, as the first CVD to develop in patients with diabetes is often heart failure rather than myocardial infarction [1], it is becoming clear that the pathology of diabetes itself causes heart failure through direct effects on cardiomyocytes and other myocardial cell types

Indications Rybelsus is approved for diabetes management, not obesity treatment

Figure 1 The distribution of tests between the public and private healthcare systems also shifted significantly

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