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Reducing adipose tissue can significantly lower systemic blood pressure and intra-glomerular pressure, which may slow the progression of renal decline

Longer acting formulations that require only monthly injection are in development

These results suggest that TB001 promotes CPT1A expression, improves lipid metabolism, and reduces PKC- expression in kidney allografts

Vacratsis, Panayiotis O

Berberine may cause gastrointestinal side effects (diarrhea, cramping), which can overlap with GLP-1-induced nausea or appetite changes, making symptom attribution complex

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