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Receptor Desensitization: Prolonged exposure to IGF1 LR3 may lead to downregulation of IGF-1 receptors or desensitization of signaling pathways

We generally see it more in middle aged patients

Some of the most common or potential side effects include: Nausea Constipation Vomiting Diarrhea Abdominal Pain Headache Indigestion Injection site reactions Dizziness Back pain Increased Lipase or Amylase Altered taste Nasopharyngitis (common cold) Passing Gas Bloating Belching Gastroenteritis Decreased appetite Fatigue Gastroesophageal reflux disease Low blood sugar (hypoglycemia) in those with type II diabetes Upset stomach These symptoms often subside as your body adjusts to the medications