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Standard precautions apply regarding hydration, protein intake, and resistance training to preserve muscle mass

If tirzepatide is producing the desired outcomes, there is no compelling reason to switch to a less proven compound with more side effects

This means food stays in the stomach longer than it should

Common Signs a Weight-Loss Plan May Be Sacrificing Muscle Patients using GLP-1 medications or aggressive dieting should watch for signs that weight loss may be moving too fast or becoming too depleting

Light stretching or gentle yoga in the evening is fine and may actually help with sleep onset

Taken together, evidence from neuroscience, human research, and clinical practice suggests meaningful overlap between obesity and addiction-related mechanisms. Lorenzo Leggio, MD, PhD, clinical director, National Institute on Drug Abuse, Bethesda, Md