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Aliment Pharmacol Ther 1991;5(2):115-25

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It was further found that miR-378a-3p and miR-182-5p negatively regulate the expression of SLC7A11 and GPX4 by directly binding to the 3 untranslated region (3UTR) of SLC7A11 and GPX4 mRNA, respectively

Continuous receptor activation isn't inherently superior to pulsed stimulation for compounds like Dihexa where the therapeutic effect derives from triggered structural changes rather than ongoing receptor occupancy

Zhang, Heming

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