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Table S1 Searching details of the meta-analysis

Multiple studies show BCAAs reduce markers of muscle damage and decrease the severity and duration of delayed-onset muscle soreness after intense exercise

Additionally, tirzepatide acts on central appetite regulation pathways in the hypothalamus, promoting satiety and reducing caloric intake, which contributes to its weight loss effects

While GLP-1/GIPs may help curb hunger, they can't substitute for the powerful effects of physical activity

These areas remain the subject of ongoing scientific investigation

Sermorelin Research# Sermorelin has a substantially more developed evidence base: Prakash and Goa (1999) : Comprehensive review establishing IV sermorelin at 1 mcg/kg as a specific diagnostic test for GH deficiency, and SC 30 mcg/kg/day as effective for pediatric growth promotion with sustained height velocity increases over 12 months