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DOI:10.1111/j.1467-2494.2005.00235.x [ Links ] 22

Our data obtained by knocking down GPx1, both in the human HEK293T cells and in rat neurons, together with the in vitro experiments, strongly suggest that endogenous -glutamylcysteine is a GPx1 cofactor for H 2 O 2 detoxification

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Dangers of this hormone include potentially increasing the risk for some cancers and reducing life span

In addition, they participated in the regulation of the expression of Bax, Bcl2, caspase-3, and cytochrome, which are highly related to apoptosis, as well as promoting a positive regulation of p53, a key molecule involved in cell death (91)