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The technology may need further development, or the right program office relationship may not yet be in place

Instead of targeting one pathway, combination protocols cover multiple mechanisms that operate in concert in natural tissue biology

miR526b and miR655 induce oxidative stress in breast cancer

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

Dysregulation and epigenetic reprogramming of NRF2 signaling axis promote acquisition of cisplatin resistance and metastasis in head and neck squamous cell carcinoma

Engineered FGF19 eliminates bile acid toxicity and lipotoxicity leading to resolution of steatohepatitis and fibrosis in mice