Brain Res 1990;535:1558.ArticlePubMed 5
A metaanalysis of 32 RCTs found that metformin, alone or with lifestyle intervention, led to greater reductions in BMI and improvements in menstrual cycle duration and frequency compared with placebo, although no additional benefits were observed over lifestyle alone
Manu P, Khan S, Radhakrishnan R, Russ MJ, Kane JM, Correll CU
Always discuss new dietary changes with a primary care physician at Macie Medical to ensure safety
CELLULAR ENERGY & IMMUNE HEALTH Promotes healthy mitochondrial function, supports natural energy production, and helps maintain a strong immune response
CONTRAINDICATIONS History of hypersensitivity reaction to tirzepatide or any of its excipients Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) PRECAUTIONS Kidney disease No dose adjustment is recommended in patients with any degree of renal impairment Liver disease No dose adjustment is recommended in patients with any degree of liver disease Stomach disorders Tirzepatide slows gastric emptying and is not recommended in patients with significant stomach disorders, including diabetic gastroparesis General anesthesia or deep sedation GLP-1 therapies, like tirzepatide, slow gastric emptying, possibly increasing the risk of residual gastric contents and pulmonary aspiration in patients receiving anesthesia or deep sedation for procedures
