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Psychopharmacology (Berl) 1987

doi: 10.1007/s43450-022-00246-w

Natividad LA, Steinman MQ, McGinn MA, Sureshchandra S, Kerr TM, Ciccocioppo R, Messaoudi I, Edwards S et al (2021) Impaired hypothalamic feedback dysregulates brain glucocorticoid signaling in genetically-selected Marchigian Sardinian alcohol-preferring rats

When dysregulated iron metabolism, impaired antioxidant defenses (such as GPX4 inactivation or system Xc inhibition), and excessive lipid peroxidation converge, ferroptosis contributes directly to cardiovascular disease pathogenesis

If emotional and physical health concerns are present, medical evaluation can lead to effective management plans

Carotenoids are also utilized in dermatological and cosmetic products as active ingredients for skin application (114)