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4.4 Anti-inflammatory effects in neuroinflammation and neurodegenerative diseases Neuroinflammation is characterized by immune cells in the central nervous system (CNS), mainly microglia and astrocytes, remaining persistently activated, which is regarded as a predominant mechanism in numerous neurodegenerative and neurological diseases (244)

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There are several potential AD biomarkers thus far identified, and these are listed with several highlighted as particularly important

Finally, the obtained core targets were imported into the Database for Annotation, Visualization and Integrated Discovery (DAVID, for Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) analysis