rxlist.com (Enlon ) Keywords Organophosphate Cholinesterase Inhibitors Echothiophate Trade Name: Phospholine Iodide Drug Class: Anticholinesterase ( Organophosphate ) Mechanism of Action: for topical use to enhance the effect of endogenously liberated acetylcholine in the iris, ciliary muscle, and other parasympathetically innervated structures of the eye Irreversible long-acting cholinesterase inhibitor It causes miosis, increases the outflow of aqueous humor, causes a fall in intraocular pressure, and potentiation of accommodation Indications: Historically used for treatment of glaucoma but currently very rarely used, and frequently regarded as obsolete for the routine treatment of glaucoma (Figure 1)
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To validate the impact of FOXO4-DRI on the P53 signaling pathway in senescent endothelial cells, Co-IP experiments were performed
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10.1097/TA.0b013e31822a3254 106 Zivanovic-PosilovicG.BalenovicD.BarisicI.StrinicD.StambolijaV.UdovicicM.et al (2016)