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336,337 Expression of antioxidants either fails to be induced or is decreased, allowing increased expression of reactive oxygen species to affect tubulointerstitial fibrosis through necrosis, apoptosis, activation of interstitial fibroblasts and pericytes, proliferation of endothelial cells, and epithelial-mesenchyme transition (figure 1)

Restored metabolic balance combined with tailored therapies reduces the likelihood of severe treatment reactions

Jul-Dec 2013;19(2):49-55

Together with a provider, individuals will be able to create a balanced and medically supervised plan suitable for their unique situation

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