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However, such a benefit might not be seen with DPP-4 inhibitors, since these drugs primarily potentiate levels of GLP-1 in the gastrointestinal tract and have modest effects on GLP-1 receptors in the systemic circulation [4]

Brain sections (40 m) were stained with free-floating method using specific anti-c-Fos (Ab-5) (417) Rabbit pAb (1:20,000

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The authors reported that Long-R3-IGF-I disappeared rapidly from circulation after 4 hours following intramuscular administration in rats, while the related analogs Des(13)-IGF-I and R3-IGF-I remained detectable for up to 24 hours [3]