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Sertraline as monotherapy caused a significant reduction in the percentage of cells in S phase in the cell line NCI-H125 ( p = 0.0020), which was further confirmed by BrdU incorporation in immunofluorescence stainings ( p = 0.0048) (Supplementary Fig

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High Oxygen Consumption: The brain consumes about 20% of the body's oxygen despite comprising only 2% of body weight, leading to a higher rate of ROS production in neurons

Glutathione also helps the liver filter out waste products and supports the immune system

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