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Studies on Sardinian shepherds with close contact with sheep (15) and school children in rural areas of Sardinia contacting both sheep and sheep dogs revealed that contact with these domestic animals might be a powerful and independent risk factor for Hp infection and accompanied dyspepsia in this Sardinian subpopulation (16)

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Glutathione depletion has been observed in various liver diseases, including fatty liver disease, viral hepatitis, and cirrhosis

110 MiR-122 is predominantly generated in the liver and constantly released into the circulation 111 and has been shown to be significantly elevated in patients with acute HF

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