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Women using testosterone therapy need careful dosing to avoid side effects like fat gain, acne, or hair growth

As research continues to evolve, healthcare providers can help patients understand current evidence, limitations, and appropriate clinical considerations

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With the involvement of SNARE proteins, mitophagosomes combine with lysosomes to form autolysosomes, ultimately degrading damaged mitochondria

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Microglial replacement using Ki20227, a CSF1R inhibitor, in 2HIT mice restored behaviors resembling psychiatric disorders, suggesting a causal contribution of 2HIT stress-reactive microglia, including SAM (Hikosaka et al., 2025)