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Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

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Epigenetic Interplay of Signal Transduction Regulation The connection between signal transduction defects and ASD pathology has opened up the treatment possibility of pharmacologically targeting these pathways, including PI3K/AKT/mTOR (mTOR), Wnt/-catenin (WNT), Notch, brain-derived neurotrophic factor (BDNF)-TrkB, sonic hedgehog, retinoic acid, bone morphogenetic protein (BMP), and MAPK/ERK pathways

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Both molecules (0.110 M) stimulated the proliferation of keratinocytes in a dose dependent manner and resulted in changes in epidermal basal cells whose integrins and p63 expression markedly increased

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