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The mechanism of uptake of DHA and EPA by the brain is unlike the uptake by the systemic tissues because of the involvement of a transporter at the blood brain barrier which is specific for the lysophosphatidylcholine (LPC)-form of DHA 23 , whereas most other tissues obtain their omega-3 FA via lipoprotein uptake or by exchange with plasma lipids

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The hydroxyl radical induces the formation of DNA-protein cross-links, single- and double-stranded breaks, lipid peroxidation, and protein fragmentation

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