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Phase 2 results have been published in obesity (Jastreboff and colleagues, N Engl J Med, 2023) and in type 2 diabetes (Rosenstock and colleagues, Lancet, 2023), and the compound has since progressed into the phase 3 TRIUMPH programme

These suddenly widely known medications are transforming the treatment of diabetes, obesity and more, yet few people know the unusual, decades-long story of how they came to be

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However, phentermine and Contrave contain different ingredients and have different effects on hunger, appetite, metabolism, and satiety

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