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However, the use of ERK1/2 or JNK inhibitors inhibited the growth of colon cancer cells in vivo and in vitro, suggesting that the activation of ERK1/2 and JNK signaling by insulin and IGF-1 is at least partially responsible for the development of T2DM-associated colon cancer (96)
However, the most interesting results were obtained when studying the influence of PO in these obesity-related metabolic impairments
doi:10.1007/s00394-025-03705-x
Therefore, it is plausible that ferroptosis may be involved in the occurrence and development of IIM, and further research is required to fully understand the inherent connection
body-composition shifts become measurable around the 8- to 12-week mark
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