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As of the date of this listing in May 2026, no New Drug Submission has been filed with Health Canada, and no equivalent New Drug Application has been filed with the FDA

Also studies on efficacy and safety in subgroup of patients of interest, mainly in subjects with renal insufficiency were important in this phase of development

In this context, GLP-1 RA treatment has been shown to reduce diastolic filling pressures and other measures of diastolic performance (Saponaro et al., 2016

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