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Researchers working on collagen peptides for joint health face similar challenges in demonstrating that orally consumed peptides reach their intended tissue targets at biologically active concentrations, a parallel problem to the topical delivery question for GHK-Cu

The decision is informed by evidence, clinical guidelines, and individual response, such as when a patient isnt sufficiently responding, experiences intolerable side effects or has a serious adverse event

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licensed medical providers make final determinations based on individual medical appropriateness