As its full safety profile remains under investigation, the following reflects current available data and known class effects: Gastrointestinal symptoms are the most common: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
GLP-1 slows gastric emptying, which prolongs the time food remains in the stomach
For weight management, lack of at least 5% weight loss by 12 weeks at the maintenance dose warrants discussion about alternative strategies or dose optimization
Retatrutide acts as a triple agonist on GLP-1, GIP, and glucagon receptors
Current evidence supports long-term use under appropriate medical supervision, and major guidelines now include these medications in long-term obesity care (WHO)
Je kunt ze niet gewoon als pil innemen, omdat ze in het maag-darmkanaal worden afgebroken